Unique strain with large, stronger cells than other probiotics.Saccharomyces boulardii lyo CNCM I-745. Be a Biotic Kid!bi-ot-ic, /bi'atik/Adjective-Proactive about health-Driven, confident, and strong 1. Buts JP, Bernasconi P, Van Craynest MP, Maldague P, De Meyer R (1986) Response of human and rat small intestinal mucosa to oral administration of Saccharomyces boulardii. Pediatr Res 20: 192-196.2. Schneider SM, Girard-Pipau F, Filippi J, Hebuterne X, Moyse D, et al. (2005) Effects if Saccharomyces boulardii on fecal short-chain fatty acids and microflora in patients on long-term total enteral nutrition. World J Gastroenterol 11: 6165-6169.3. Swidsinski A, Leoning-Baucke V, Verstraelen H, Osowska S, Doerffel Y (2008) Biostructure of fecal microbiota in healthy subjects and patients with chronic idiopathic diarrhea. Gastroenterology: 135(2): 568-579.4. Martins FS, Silva AA, Vieira AT, Barbosa FH. Arantes RM, et al. (2009) Comparative study of Bifidobacterium animalis, Escherichia coli, Lactobacillus casei and Saccharomyces boulardii probiotic properties. Arch Microbiol 191: 623-630.5. Klein SM, Elmer GW, McFarland LV, Surawicz CM, Levy RH (1993) Recovery and elimination of the biotherapeutic agent, Saccharomyces boulardii, in healthy human volunteers. Pharm Res 10: 1615-1619. Boost Natural Immune Response Strengthen Digestive Balance Support Your Active Lifestyle Appropriate for Lactose Intolerance I am Biotic For Men and Women Double the Dose in One Convenient Sachet