Grain, wheat, corn and soy free. Made with real chicken. Reduces plaque and freshens breath. Easy as one, chew, three. These tough and tasty chews are designed to combine with our innovative triple enzyme toothpaste. Together, they're an effective way to freshen breath and reduce plague on your dog's teeth. These dental chews are made In the USA with real chicken and without any artificial colors or flavors. They're also grain, wheat, corn and soy-free. Fill pocket to top with Bright Toothpaste (toothpaste sold separately).Chewing and chomping reduces plaque. Made in the USA. Calorie Content (Calculated Metabolizable Energy): 2,845 kcal/kg, 65 kcal/treat ME.